Anordrin

Anordrin is a contraceptive agent. Anordrin exhibits estrogenicites and can induce decrease in serum progesterone levels in rat models. Anordrin inhibits endometrial epithelial cell mitosis and NAFLD induced by Tamoxifen (HY-13757A) in mouse uterus and liver as an anti-estrogenic and estrogenic agent[1][2].

Product Specifications

CAS Number

[56470-64-5]

UNSPSC

12352211

Target

Progesterone Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Smiles

C[C@@]12[C@](CC[C@]2(C#C)OC(CC)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](C[C@](C#C)(C4)OC(CC)=O)([H])CC3)C)([H])CC1

Molecular Formula

C28H38O4

Molecular Weight

438.60

References & Citations

[1]Liu, C. Q., et al., (1985) . Effects of anordrin and its analogue on antifertility. Contraception, 32 (3), 301-309. |[2]Gu, W., et al., (2017) . Anordrin Eliminates Tamoxifen Side Effects without Changing Its Antitumor Activity. Scientific reports, 7, 43940.