SUN-N8075 (dimethanesulfonate)

SUN-N8075 dimethanesulfonate is a radical scavenger with antioxidant and neuroprotective effect. SUN-N8075 dimethanesulfonate can inhibit apoptosis and ROS production. SUN-N8075 dimethanesulfonate can protect against 6-OHDA (HY-B1081) -induced cell death. SUN-N8075 dimethanesulfonate can be used for the research of neurological disease, such as Parkinson's disease[1][2].

Product Specifications

CAS Number

[224450-56-0]

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

CC(C(C)=C(N)C(C)=C1)=C1OC[C@@H](O)CN(CC2)CCN2C(C=C3)=CC=C3CC4=CC=C(F)C=C4.CS(=O)(O)=O.CS(=O)(O)=O

Molecular Formula

C31H44FN3O8S2

Molecular Weight

669.82

References & Citations

[1]Oyagi A, et al. Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease. Brain Res. 2008 Jun 12;1214:169-76.|[2]Akane M, et al. SUN N8075, a novel radical scavenger, protects against retinal cell death in mice. Neurosci Lett. 2011 Jan 13;488 (1) :87-91.