TEI-6122
TEI-6122 is a 7-thiaprostaglandin E1 derivative. TEI-6122 can reduce urinary protein and suppressthe increase of blood urea nitrogen. TEI-6122 can inhibit monocyte chemoattractant protein-1 induced chemotaxis. TEI-6122 can be used for the research of inflammation, such as nephritis[1][2].
Product Specifications
CAS Number
83058-69-9
Product Name Alternative
TFC 612
UNSPSC
12352100
Target
Drug Derivative
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
COC(CCCCCS[C@@H]1[C@H]([C@H](O)CC1=O)/C=C/[C@@H](O)C[C@H](C)CCCC)=O
Molecular Formula
C22H38O5S
Molecular Weight
414.60
References & Citations
[1]Nagamatsu T, et al. Antinephritic effects of PGE1 and thiaprostaglandin E1, TEI-5178 and TEI-6122, on crescentic-type anti-GBM nephritis in rats. Jpn J Pharmacol. 1989 Dec;51 (4) :521-30.|[2]Tanaka H, et al. The effect of a synthetic 7-thiaprostaglandin E1 derivative, TEI-6122, on monocyte chemoattractant protein-1 induced chemotaxis in THP-1 cells. Br J Pharmacol. 1995 Oct;116 (4) :2298-302.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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