Lortalamine
Lortalamine (LM 1404) is a selective norepinephrine transporter inhibitor with an IC50 of [1][2].
Product Specifications
CAS Number
70384-91-7
Product Name Alternative
LM 1404
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Monoamine Transporter
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease; Neurological Disease
Smiles
O=C1N[C@@]23[C@@](CN(CC3)C)([H])[C@](C1)([H])C4=CC(Cl)=CC=C4O2
Molecular Formula
C15H17ClN2O2
Molecular Weight
292.76
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lin KS, et al. Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R) -nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons. Bioorg Med Chem. 2005 Aug 1;13 (15) :4658-66. |[2]Depin JC, et al. Pharmacology of lortalamine, a new potent non-tricyclic antidepressant. Arzneimittelforschung. 1985;35 (11) :1655-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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