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Amocarzine

Amocarzine (CGP 6140) is an orally active antifilarial agent. Amocarzine can result in the swelling of mitochondrion and inhibit respiration and other associated metabolic functions. Amocarzine can be used for the research of infection[1].

Product Specifications

CAS Number

[36590-19-9]

Product Name Alternative

CGP 6140

UNSPSC

12352005

Target

Mitochondrial Metabolism; Parasite

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

S=C(N1CCN(C)CC1)NC2=CC=C(NC3=CC=C([N+]([O-])=O)C=C3)C=C2

Molecular Formula

C18H21N5O2S

Molecular Weight

371.46

References & Citations

[1]Köhler P, et al. Activity, mechanism of action and pharmacokinetics of 2-tert-butylbenzothiazole and CGP 6140 (amocarzine) antifilarial drugs. Acta Trop. 1992 Aug;51 (3-4) :195-211.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

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