Proterguride
Proterguride is a potent dopamine receptor agonist. Proterguride also shows antagonistic properties at the histamine H (1) receptor and alpha (1) -adrenoceptor and partially agonize serotonergic 5-HT2A/B receptor. Proterguride can be used for the research of neurological disease, such as Parkinson's disease [1].
Product Specifications
CAS Number
77650-95-4
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CCCN1[C@@](C2)([H])[C@@](C[C@H](NC(N(CC)CC)=O)C1)([H])C3=C4C2=CNC4=CC=C3
Molecular Formula
C22H32N4O
Molecular Weight
368.52
References & Citations
[1]Schurad B, et al. Proterguride, a highly potent dopamine receptor agonist promising for transdermal administration in Parkinson's disease: interactions with alpha (1) -, 5-HT (2) - and H (1) -receptors. Life Sci. 2006 Apr 11;78 (20) :2358-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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