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Zifrosilone

Zifrosilone is an orally active acetylcholinesterase (AChE) inhibitor with a mean maximum inhibition of 20.9% at 10 mg. Zifrosilone can be used for the research of neurological disease[1].

Product Specifications

CAS Number

[132236-18-1]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

FC(F)(F)C(C1=CC([Si](C)(C)C)=CC=C1)=O

Molecular Formula

C11H13F3OSi

Molecular Weight

246.30

References & Citations

[1]Cutler NR, et al. Acetylcholinesterase inhibition by zifrosilone: pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther. 1995 Jul;58 (1) :54-61.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

AChE

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