Cystemustine
Cystemustine is a DNA inhibitor (a chloroethyl nitrosourea, CENU) . Cystemustine can cause DNA cross-linking, thereby inhibiting the proliferation of tumor cells. Cystemustine can also exert cytotoxic effects by interfering with the cell cycle, inducing cell re-differentiation, and altering phospholipid metabolism. Cystemustine exhibits high anti-tumor activity and a relatively short plasma half-life in mice. Cystemustine can be used for the study of various malignant tumors, including melanoma, glioma, renal cancer, head and neck cancer, and colorectal cancer, etc[1][2][3][4][5][6].
Product Specifications
CAS Number
79955-36-5
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker; DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CS(CCNC(N(N=O)CCCl)=O)(=O)=O
Molecular Formula
C6H12ClN3O4S
Molecular Weight
257.70
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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