Nebicapone (Standard)
Nebicapone (Standard) is the analytical standard of Nebicapone. This product is intended for research and analytical applications. Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease[1].
Product Specifications
CAS Number
274925-86-9
Product Name Alternative
BIA 3-202 (Standard)
UNSPSC
12352005
Target
COMT; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Metabolic Disease
Smiles
O=C(C1=CC([N+]([O-])=O)=C(O)C(O)=C1)CC2=CC=CC=C2
Molecular Formula
C14H11NO5
Molecular Weight
273.24
References & Citations
[1]Loureiro AI, et al. Human metabolism of nebicapone (BIA 3-202), a novel catechol-o-methyltransferase inhibitor: characterization of in vitro glucuronidation. Drug Metab Dispos. 2006 Nov;34 (11) :1856-62.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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