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Penclomedine

Penclomedine (NSC 338720), a synthetic alpha-picoline derivative, is an orally active antitumor agent. Penclomedine has a strong inhibitory effect on breast cancer cells, such as CD8F1 and MX-1 cells[1].

Product Specifications

CAS Number

[108030-77-9]

Product Name Alternative

NSC 338720

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

ClC1=C(OC)N=C(C(Cl)(Cl)Cl)C(Cl)=C1OC

Molecular Formula

C8H6Cl5NO2

Molecular Weight

325.40

References & Citations

[1]Plowman J, et al. Preclinical antitumor activity of an alpha-picoline derivative, penclomedine (NSC 338720), on human and murine tumors. Cancer Res. 1989 Apr 15;49 (8) :1909-15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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