Aurothiomalate tetramer (sodium)
Aurothiomalate tetramer sodium, an Aurothiomalate sodium (HY-106381) tetrameric form, is antiarthritic gold agent. Aurothiomalate sodium is a potent and selective oncogenic PKCι signaling inhibitor[1].
Product Specifications
UNSPSC
12352211
Target
PKC
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
98.0
Smiles
O=C(O[Na])C(S[Au])CC(O[Na])=O.[4]
References & Citations
[1]Farivash Darabi, et al. Reactions of model proteins with aurothiomalate, a clinically established gold (I) drug: The comparison with auranofin. J Inorg Biochem. 2015 Aug:149:102-7.|[2]Roderick P Regala, et al. Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells. Cancer Res. 2008 Jul 15;68 (14) :5888-95.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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