Aurothiomalate tetramer (sodium)

Aurothiomalate tetramer sodium, an Aurothiomalate sodium (HY-106381) tetrameric form, is antiarthritic gold agent. Aurothiomalate sodium is a potent and selective oncogenic PKCι signaling inhibitor[1].

Product Specifications

UNSPSC

12352211

Target

PKC

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

98.0

Smiles

O=C(O[Na])C(S[Au])CC(O[Na])=O.[4]

References & Citations

[1]Farivash Darabi, et al. Reactions of model proteins with aurothiomalate, a clinically established gold (I) drug: The comparison with auranofin. J Inorg Biochem. 2015 Aug:149:102-7.|[2]Roderick P Regala, et al. Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells. Cancer Res. 2008 Jul 15;68 (14) :5888-95.