Glenvastatin

Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia[1]

Product Specifications

CAS Number

[122254-45-9]

Product Name Alternative

HR 780

UNSPSC

12352005

Target

HMG-CoA Reductase (HMGCR)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O[C@@H](CC1=O)C[C@H](O1)/C=C/C2=C(C(C)C)N=C(C3=CC=CC=C3)C=C2C4=CC=C(F)C=C4

Molecular Formula

C27H26FNO3

Molecular Weight

431.50

References & Citations

[1]Sobotta L, et al. Photochemical activity of glenvastatin, a HMG-CoA reductase inhibitor[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2011, 224 (1) : 1-7.