Glenvastatin
Glenvastatin (HR 780) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Glenvastatin can reduces plasma total cholesterol and phospholipid levels and liver cholesterol contents. Glenvastatin does not increase the contents of cholesterol and total bile acid in the gallbladder bile. Glenvastatin can be used for the research of hyperlipemia[1]
Product Specifications
CAS Number
122254-45-9
Product Name Alternative
HR 780
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O[C@@H](CC1=O)C[C@H](O1)/C=C/C2=C(C(C)C)N=C(C3=CC=CC=C3)C=C2C4=CC=C(F)C=C4
Molecular Formula
C27H26FNO3
Molecular Weight
431.50
References & Citations
[1]Sobotta L, et al. Photochemical activity of glenvastatin, a HMG-CoA reductase inhibitor[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2011, 224 (1) : 1-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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