DL-Buthionine- (S, R) -sulfoximine (Standard)

DL-Buthionine- (S, R) -sulfoximine (Standard) is the analytical standard of DL-Buthionine- (S, R) -sulfoximine. This product is intended for research and analytical applications. DL-Buthionine- (S, R) -sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.

Product Specifications

CAS Number

[5072-26-4]

Product Name Alternative

Buthionine sulfoximine (Standard) ; BSO (Standard)

UNSPSC

12352211

Target

Ferroptosis; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Smiles

OC(C(N)CCS(CCCC)(=N)=O)=O

Molecular Formula

C8H18N2O3S

Molecular Weight

222.31

References & Citations

[1]Griffith OW, et al. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine) . J Biol Chem. 1979 Aug 25;254 (16) :7558-60.|[2]Vanhoefer U, et al. d, l-buthionine- (S, R) -sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors. Clin Cancer Res. 1996 Dec;2 (12) :1961-8.