DL-Buthionine- (S, R) -sulfoximine (hydrochloride) (Standard)

DL-Buthionine- (S, R) -sulfoximine (hydrochloride) (Standard) is the analytical standard of DL-Buthionine- (S, R) -sulfoximine (hydrochloride) . This product is intended for research and analytical applications. DL-Buthionine- (S, R) -sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.

Product Specifications

Product Name Alternative

Buthionine sulfoximine (hydrochloride) (Standard) ; BSO (hydrochloride) (Standard)

UNSPSC

12352211

Target

Ferroptosis; Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Smiles

OC(C(N)CCS(CCCC)(=N)=O)=O.[H]Cl

Molecular Formula

C8H19ClN2O3S

Molecular Weight

258.77

References & Citations

[1]Griffith OW, et al. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine) . J Biol Chem. 1979 Aug 25;254 (16) :7558-60.|[2]Vanhoefer U, et al. d, l-buthionine- (S, R) -sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors. Clin Cancer Res. 1996 Dec;2 (12) :1961-8.