MK-0963
MK-0963 is a steroidal 5α-reductase inhibitor. MK-0963 reduces serum dihydrotestosterone (DHT) concentrations in a dose-dependent manner. MK-0963 can be used for the study of dihydrotestosterone-related diseases such as benign prostate hyperplasia (BPH) [1].
Product Specifications
CAS Number
[103497-68-3]
Product Name Alternative
L 654066
UNSPSC
12352005
Target
5 alpha Reductase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
C[C@@]12[C@](CC[C@@H]2C(CC(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](NC(C=C4)=O)([H])CC3)C)([H])CC1
Molecular Formula
C23H35NO2
Molecular Weight
357.53
References & Citations
[1]Depré M, et al. Pharmacodynamics and tolerability of L-654,066, a steroid 5 alpha-reductase inhibitor, in men. Clin Pharmacol Ther. 1992 Oct;52 (4) :409-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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