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MK-0963

MK-0963 is a steroidal 5α-reductase inhibitor. MK-0963 reduces serum dihydrotestosterone (DHT) concentrations in a dose-dependent manner. MK-0963 can be used for the study of dihydrotestosterone-related diseases such as benign prostate hyperplasia (BPH) [1].

Product Specifications

CAS Number

[103497-68-3]

Product Name Alternative

L 654066

UNSPSC

12352005

Target

5 alpha Reductase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

C[C@@]12[C@](CC[C@@H]2C(CC(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](NC(C=C4)=O)([H])CC3)C)([H])CC1

Molecular Formula

C23H35NO2

Molecular Weight

357.53

References & Citations

[1]Depré M, et al. Pharmacodynamics and tolerability of L-654,066, a steroid 5 alpha-reductase inhibitor, in men. Clin Pharmacol Ther. 1992 Oct;52 (4) :409-12.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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