Andolast (free base) (Standard)

Andolast (free base) (Standard) is the analytical standard of Andolast (free base) . This product is intended for research and analytical applications. Andolast (CR 2039) (free base) is an anti-allergic agent. Andolast can inhibit cAMP-phosphodiesterase with an IC50 value of 50 μM. Andolast can be used for the research of asthma[1].

Product Specifications

CAS Number

[132640-22-3]

Product Name Alternative

CR 2039 (free base) (Standard) ; Dizolast (free base) (Standard)

UNSPSC

12352005

Target

Phosphodiesterase (PDE) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(C1=CC=C(C2=NN=NN2)C=C1)NC3=CC=C(C4=NN=NN4)C=C3

Molecular Formula

C15H11N9O

Molecular Weight

333.31

References & Citations

[1]Revel L, Colombo S, Ferrari F, Folco G, Rovati LC, Makovec F. CR 2039, a new bis- (1H-tetrazol-5-yl) phenylbenzamide derivative with potential for the topical treatment of asthma. Eur J Pharmacol. 1992;229 (1) :45-53. |[2]Czuczwar SJ, Gasior M, Kozicka M, Pietrasiewicz T, Turski WA, Kleinrok Z. A potential anti-asthmatic drug, CR 2039, enhances the anticonvulsive activity of some antiepileptic drugs against pentetrazol in mice. Eur Neuropsychopharmacol. 1998;8 (3) :233-238.