Sezolamide

Sezolamide (MK 417 free base) is a potent topical carbonic anhydrase inhibitor. Sezolamide can be used in studies to reduce intraocular pressure[1].

Product Specifications

CAS Number

[123308-22-5]

Product Name Alternative

MK 417 (free base) ; (S) -MK-927 (free base)

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

O=S1(C2=C(C=C(S2)S(N)(=O)=O)[C@H](CC1)NCC(C)C)=O

Molecular Formula

C11H18N2O4S3

Molecular Weight

338.47

References & Citations

[1]Gunning FP, et al. Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study. Graefes Arch Clin Exp Ophthalmol. 1993 Jul;231 (7) :384-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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