(Rac) -Sezolamide (hydrochloride)
(Rac) -Sezolamide hydrochloride (MK-927; (Rac) -MK 417) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM) . (Rac) -Sezolamide hydrochloride has a topical intraocular pressure (IOP) lowering effect. (Rac) -Sezolamide hydrochloride can be used in glaucoma research[1].
Product Specifications
CAS Number
[126453-94-9]
Product Name Alternative
MK-927; (Rac) -MK 417
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Smiles
O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O.Cl
Molecular Formula
C11H19ClN2O4S3
Molecular Weight
374.93
References & Citations
[1]Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6 (1) :9-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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