(Rac) -Sezolamide (hydrochloride)
(Rac) -Sezolamide hydrochloride (MK-927; (Rac) -MK 417) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM) . (Rac) -Sezolamide hydrochloride has a topical intraocular pressure (IOP) lowering effect. (Rac) -Sezolamide hydrochloride can be used in glaucoma research[1].
Product Specifications
CAS Number
126453-94-9
Product Name Alternative
MK-927; (Rac) -MK 417
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Smiles
O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O.Cl
Molecular Formula
C11H19ClN2O4S3
Molecular Weight
374.93
References & Citations
[1]Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6 (1) :9-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040994-500 1x 500 µL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880352-500 1x 500 µL
CD31 / PECAM-1 (158-2B3), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680965-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681120-500 1x 500 µL
Ep-CAM / CD326 (EGP40/1120), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details