(Rac) -Sezolamide
(Rac) -Sezolamide (MK-927 (free base) ; (Rac) -MK 417 (free base) ) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM) . (Rac) -Sezolamide has a topical intraocular pressure (IOP) lowering effect. (Rac) -Sezolamide can be used in glaucoma research[1].
Product Specifications
CAS Number
123291-07-6
Product Name Alternative
MK-927 (free base) ; (Rac) -MK 417 (free base)
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Smiles
O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O
Molecular Formula
C11H18N2O4S3
Molecular Weight
338.47
References & Citations
[1]Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6 (1) :9-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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