Ipazilide (fumarate)

Ipazilide fumarate (Win 54177-4 fumarate) is an antiarrhythmic agent. Ipazilide fumarate reduces K+- depolarized tone. Ipazilide fumarate prolongs ventricular refractoriness and possesses antiectopic activity[1][2].

Product Specifications

CAS Number

[115436-74-3]

Product Name Alternative

Win 54177-4 (fumarate)

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

CCN(CC)CCCNC(CN1C(C2=CC=CC=C2)=C(C3=CC=CC=C3)C=N1)=O.O=C(O)/C=C/C(O)=O

Molecular Formula

C28H34N4O5

Molecular Weight

506.59

References & Citations

[1]Greener Y, et al. Chronic (1-year) safety evaluation of ipazilide fumarate, an antiarrhythmic agent, administered orally to rats. Fundam Appl Toxicol. 1993 Feb;20 (2) :147-54. |[2]Ezrin A M, et al. In vivo and in vitro effects of the novel antiarrhythmic ipazilide on cardiac and vascular smooth muscle function[J]. Drug development research, 1992, 27 (2) : 107-120.