EM-523
EM-523 is a motilin agonist and an erythromycin derivative. EM-523 has pED50 values of 8.19 and 6.08 for promoting contractions in rabbit small intestinal tissue and human duodenal tissue, respectively. EM-523 can be used in the research of gastrointestinal diseases[1].
Product Specifications
CAS Number
[110205-60-2]
UNSPSC
12352005
Target
Motilin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Smiles
C[C@]1(OC([C@@H]([C@H]([C@](O)([C@H](OC([C@@H]([C@H]([C@@H]2C)O[C@H]3C[C@](C)([C@H]([C@@H](O3)C)O)OC)C)=O)CC)C)O)C)=C(C1)C)[C@@H]2O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)CC)O
Molecular Formula
C38H67NO12
Molecular Weight
729.94
References & Citations
[1]Depoortere I, et al. The erythromycin derivative EM-523 is a potent motilin agonist in man and in rabbit. Peptides. 1990 May-Jun;11 (3) :515-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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