ME-1228
ME-1228 is an antibacterial agent and sulfur-containing analogue of OCP 9-176. ME 1228 is generally twofold more active than OCP 9-176 against Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Providencia stuartii, Proteus vulgaris, and Serratia marcescens. ME-1228 has antibacterial activity against E. coli UB 1005, P. aeruginosa K779K, and P. aeruginosa E4, with MICs of 0.25, 0.25, and 1 μg/mL, respectively[1].
Product Specifications
CAS Number
115369-52-3
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
[O-]C(C1=C(CSC2=CC=[N+](CC)C=C2)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\O[C@@H](C)C(O)=O)=O)([H])N1C3=O)=O
Molecular Formula
C23H24N6O7S3
Molecular Weight
592.67
References & Citations
[1]Gu JW, et al. In vitro activity of an oxycephem OCP 9-176 compared with its sulfur analog and other beta-lactams. Diagn Microbiol Infect Dis. 1991 Mar-Apr;14 (2) :135-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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