HMR-3339

HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy[1][2].

Product Specifications

CAS Number

[214140-47-3]

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology; Metabolic Disease

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@](C4=CC=C(O)C(Cl)=C4CC3)([H])[C@@H](C5=CC=C(OCCN(CC)CC)C=C5)C1

Molecular Formula

C30H40ClNO3

Molecular Weight

498.10

References & Citations

[1]Ammann P, et al. A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats. Bone. 2004 Jul;35 (1) :153-61. |[2]Vogelvang TE, et al. HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women. Fertil Steril. 2004 Dec;82 (6) :1540-9.