HMR-3339
HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy[1][2].
Product Specifications
CAS Number
214140-47-3
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology; Metabolic Disease
Smiles
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@](C4=CC=C(O)C(Cl)=C4CC3)([H])[C@@H](C5=CC=C(OCCN(CC)CC)C=C5)C1
Molecular Formula
C30H40ClNO3
Molecular Weight
498.10
References & Citations
[1]Ammann P, et al. A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats. Bone. 2004 Jul;35 (1) :153-61. |[2]Vogelvang TE, et al. HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women. Fertil Steril. 2004 Dec;82 (6) :1540-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Estrogen receptor
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