Allotrap 07
Allotrap 07 is a synthetic peptide composed of residues 75-84 of HLA-B7, a class I MHC molecule. Allotrap 07 combined with Cyclosporin A induces donor-specific tolerance in rat cardiac allografts, significantly prolonging graft survival[1].
Product Specifications
CAS Number
151232-75-6
UNSPSC
12352005
Target
MHC
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C53H90N20O16
Molecular Weight
1263.41
References & Citations
[1]Masroor S, et al. Induction of tolerance in rodent cardiac allotransplantation using an MHC class I-derived peptide and cyclosporin A. Ann Thorac Surg. 1998 Jan;65 (1) :144-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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