E-5842 (citrate)
E-5842 citrate is a σ receptor ligand (Ki: 4 nM for σ1 receptor) . E-5842 citrate increases levels of Fos in the medial prefrontal cortex and the nucleus accumbens, without affecting the levels of the protein in the striatum. E-5842 citrate can be used in the research of psychiatric disorders[1].
Product Specifications
CAS Number
220120-14-9
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
FC1=CC=C(C=C1)C2=CCN(CC2)CCCCN3N=CN=C3.O=C(O)CC(O)(CC(O)=O)C(O)=O
Molecular Formula
C23H29FN4O7
Molecular Weight
492.50
References & Citations
[1]Guitart X, et al. The effect of E-5842, a sigma receptor ligand and potential atypical antipsychotic, on Fos expression in rat forebrain. Eur J Pharmacol. 1998 Dec 18;363 (2-3) :127-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042744-500 1x 500 µL
PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) (PDL1/2744), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
LC401066 20 µg
VMAT2 (SLC18A2) (NM_003054) Human Over-expression Lysate
Sign In for Pricing
View Details 
