Bimosiamose (Standard)

Bimosiamose (Standard) is the analytical standard of Bimosiamose. This product is intended for research and analytical applications. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects[1].

Product Specifications

CAS Number

[187269-40-5]

Product Name Alternative

TBC-1269 (Standard)

UNSPSC

12352005

Target

P-selectin; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

OC[C@H]([C@@H](O)[C@H](O)[C@@H]1O)O[C@@H]1OC(C=C2)=C(C3=CC(CC(O)=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O)=O)=CC=C5)=C4O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@@H]6O)CO

Molecular Formula

C46H54O16

Molecular Weight

862.91

References & Citations

[1]Palma-Vargas JM, et al. Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion. J Am Coll Surg. 1997 Oct;185 (4) :365-72.