Roxindole (hydrochloride) (Standard)
Roxindole (hydrochloride) (Standard) is the analytical standard of Roxindole (hydrochloride) . This product is intended for research and analytical applications. Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM) . Antipsychotic and antidepressant activities[1][2][3].
Product Specifications
CAS Number
108050-82-4
Product Name Alternative
EMD 38362 (Standard)
UNSPSC
12352005
Target
Dopamine Receptor; Reference Standards; Serotonin Transporter
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
OC1=CC2=C(C=C1)NC=C2CCCCN3CCC(C4=CC=CC=C4)=CC3.[H]Cl
Molecular Formula
C23H27ClN2O
Molecular Weight
382.93
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Isoform
5-HT1 Receptor
Frequently Asked Questions
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