Losoxantrone (hydrochloride)
Losoxantrone hydrochloride (CI 941 hydrochloride) is a DNA-binding agent. Losoxantrone hydrochloride has broad-spectrum antitumour activity. Losoxantrone hydrochloride induces dose-dependent leukopenia[1].
Product Specifications
Product Name Alternative
CI 941 (hydrochloride) ; DUP 94 (hydrochloride)
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
OCCNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4)C2=O.Cl.Cl
Molecular Formula
C22H29Cl2N5O4
Molecular Weight
498.40
References & Citations
[1]Graham MA, et al. The pharmacokinetics and toxicity of the anthrapyrazole anti-cancer drug CI-941 in the mouse: a guide for rational dose escalation in patients. Cancer Chemother Pharmacol. 1989;23 (1) :8-14.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106091B/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[88303-61-1]
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