Losoxantrone
Losoxantrone (CI 941) is a DNA-binding agent. Losoxantrone has broad-spectrum antitumour activity. Losoxantrone induces dose-dependent leukopenia[1].
Product Specifications
CAS Number
88303-60-0
Product Name Alternative
CI 941; DuP-941; Biantrazole
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCNCCO)C=CC=C2O
Molecular Formula
C22H27N5O4
Molecular Weight
425.48
References & Citations
[1]Graham MA, et al. The pharmacokinetics and toxicity of the anthrapyrazole anti-cancer drug CI-941 in the mouse: a guide for rational dose escalation in patients. Cancer Chemother Pharmacol. 1989;23 (1) :8-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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