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Losoxantrone

Losoxantrone (CI 941) is a DNA-binding agent. Losoxantrone has broad-spectrum antitumour activity. Losoxantrone induces dose-dependent leukopenia[1].

Product Specifications

CAS Number

88303-60-0

Product Name Alternative

CI 941; DuP-941; Biantrazole

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCNCCO)C=CC=C2O

Molecular Formula

C22H27N5O4

Molecular Weight

425.48

References & Citations

[1]Graham MA, et al. The pharmacokinetics and toxicity of the anthrapyrazole anti-cancer drug CI-941 in the mouse: a guide for rational dose escalation in patients. Cancer Chemother Pharmacol. 1989;23 (1) :8-14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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