Pazelliptine
Pazelliptine (Pazellipticine) is a DNA topoisomerase inhibitor and antitumour agent[1][2].
Product Specifications
CAS Number
65222-35-7
Product Name Alternative
Pazellipticine; BD-40
UNSPSC
12352005
Target
Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CCN(CC)CCCNC1=NC=CC2=C1C=C3C4=CN=CC=C4NC3=C2C
Molecular Formula
C22H27N5
Molecular Weight
361.48
References & Citations
[1]Balosso J, et al. Additive and supraadditive interaction between ionizing radiation and pazelliptine, a DNA topoisomerase inhibitor, in Chinese hamster V-79 fibroblasts. Cancer Res. 1991 Jun 15;51 (12) :3204-11. |[2]Fontaine-Aupart M P, et al. Proton and charge transfer in the intercalating antitumour drug pazelliptine. Journal of the Chemical Society, Perkin Transactions 2, 1996 (8) : 1767-1774.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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