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YM 133

YM 133 (IMC-XV) is a semisynthetic macrolide antibiotic with potent bactericidal activity. YM 133 shows activity against Erythromycin (HY-B0220) -, Josamycin (HY-B1920) -, and rokitamycin-resistant (MIC ≥ 100 μg/mL) strains of staphylococci, streptococci, Bacteroides spp., and Clostridium spp. YM 133 exhibits excellent activity against macrolide-resistant strains and against anaerobes. YM 133 can be used for antibacterial research[1].

Product Specifications

CAS Number

[103360-00-5]

Product Name Alternative

IMC-XV

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CN(C)C(C(C(OC1C(CC(C(/C=C\C(C)=C/C(COC2C(C(C(O)C(C)O2)OC)OC)C(CC)OC(CC(O)C1C)=O)=O)C)CC=O)OC3C)O)C3OC4CC(O)(C(OC(CC5=CC=C(OC)C=C5)=O)C(C)O4)C

Molecular Formula

C55H85NO19

Molecular Weight

1064.26

References & Citations

[1]Terasawa T, Watanabe M, Okubo T, Mitsuhashi S. In vitro activity of YM133, a new semisynthesized macrolide. Antimicrob Agents Chemother. 1991 Jul;35 (7) :1370-5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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