NSC 303861
NSC 303861 is an L-glutamine antagonist. NSC 303861 selectively inhibits glutamine dependent enzymes in purine nucleotide synthesis without affecting pyrimidine synthase. NSC 303861 has significant cytotoxicity against liver cancer 3924A cells (LC50 = 6 µM) . NSC 303861 can be used for cancer research[1].
Product Specifications
CAS Number
[51785-99-0]
UNSPSC
12352211
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CCOC([C@@H](N)CSC(NC)=O)=O.Cl
Molecular Formula
C7H15ClN2O3S
Molecular Weight
242.72
References & Citations
[1]Jayaram HN, et al. Oncolytic activity and mechanism of action of a novel L-cysteine derivative, L-cysteine, ethyl ester, S- (N-methylcarbamate) monohydrochloride. Cancer Chemother Pharmacol. 1990;26 (2) :88-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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