Tomoxiprole
Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) [1][2].
Product Specifications
CAS Number
76145-76-1
Product Name Alternative
MDL 035
UNSPSC
12352005
Target
COX
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
CC(N1C2=CC=C(C=CC=C3)C3=C2N=C1C4=CC=C(OC)C=C4)C
Molecular Formula
C21H20N2O
Molecular Weight
316.40
References & Citations
[1]Assandri A, et al. Pharmacokinetics and metabolism of tomoxiprole, a new analgesic antiinflammatory agent, in the rat. Eur J Drug Metab Pharmacokinet. 1985 Apr-Jun;10 (2) :161-70. |[2]West RE Jr, et al. Tomoxiprole selectively inhibits cyclooxygenase-2. Prostaglandins. 1997 Dec;54 (6) :891-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
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