Wy 27569
Wy 27569 is an orally active vascular selective calcium channel blocker that can effectively lower blood pressure. Wy 27569 is a thromboxane synthase inhibitor that can reshape prostaglandin balance, reduce pro thrombotic TXA2, and increase anti thrombotic PGI2. Wy 27569 can be used for research on cardiovascular diseases such as hypertension and angina[1].
Product Specifications
CAS Number
103417-69-2
UNSPSC
12352005
Target
Calcium Channel; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
CCOC(C1=C(CN2C=CN=C2)NC(C)=C(C(OC)=O)C1C3=CC([N+]([O-])=O)=CC=C3)=O
Molecular Formula
C21H22N4O6
Molecular Weight
426.42
References & Citations
[1]Ennis C, et al. Pharmacologic effects of Wy 27569: a combined calcium channel blocker and thromboxane synthetase inhibitor. J Cardiovasc Pharmacol. 1989 Apr;13 (4) :511-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Calcium Channel; TXA2/TP
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