Wy 27569

Wy 27569 is an orally active vascular selective calcium channel blocker that can effectively lower blood pressure. Wy 27569 is a thromboxane synthase inhibitor that can reshape prostaglandin balance, reduce pro thrombotic TXA2, and increase anti thrombotic PGI2. Wy 27569 can be used for research on cardiovascular diseases such as hypertension and angina[1].

Product Specifications

CAS Number

[103417-69-2]

UNSPSC

12352005

Target

Calcium Channel; Prostaglandin Receptor

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

CCOC(C1=C(CN2C=CN=C2)NC(C)=C(C(OC)=O)C1C3=CC([N+]([O-])=O)=CC=C3)=O

Molecular Formula

C21H22N4O6

Molecular Weight

426.42

References & Citations

[1]Ennis C, et al. Pharmacologic effects of Wy 27569: a combined calcium channel blocker and thromboxane synthetase inhibitor. J Cardiovasc Pharmacol. 1989 Apr;13 (4) :511-9.