Sulfatroxazole-d4
Sulfatroxazole-d4 (Isosulfafurazole-d4) is the deuterium labeled Sulfatroxazole. Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC50 of 0.26 μM).
Product Specifications
Product Name Alternative
Isosulfafurazole-d4
UNSPSC
12352005
Target
Endothelin Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NOC(C)=C2C)=O
Molecular Formula
C11H9D4N3O3S
Molecular Weight
271.33
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Stein P D, et al. Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists[J]. Journal of medicinal chemistry, 1995, 38 (8) : 1344-1354.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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