Cloticasone propionate

Cloticasone propionate (CCI 18773) is an intermediate in the synthesis of Fluticasone propionate (HY-B0154) . Fluticasone propionate is a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist[1].

Product Specifications

CAS Number

[80486-69-7]

Product Name Alternative

CCI 18773; S-Chlorofluticasone propionate

UNSPSC

12352100

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Others

Smiles

CCC(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@@](F)([C@@]4(C([C@@H](F)C3)=CC(C=C4)=O)C)[C@@H](O)C2)([H])C[C@H]1C)C)C(SCCl)=O)=O

Molecular Formula

C25H31ClF2O5S

Molecular Weight

517.03

References & Citations

[1]Bryson HM, et, al. Intranasal fluticasone propionate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in allergic rhinitis. Drugs. 1992 May;43 (5) :760-75.