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Delavirdine (Standard)

Delavirdine (Standard) is the analytical standard of Delavirdine. This product is intended for research and analytical applications. Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) . Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26?μM) over DNA polymerase?α? (IC50=440 μM) and polymerase?δ (IC50>550?μM) . Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs[1].

Product Specifications

CAS Number

136817-59-9

Product Name Alternative

U 90152 (Standard) ; BHAP-U 90152 (Standard)

UNSPSC

12352005

Target

HIV; Reference Standards; Reverse Transcriptase

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=S(NC1=CC=C(NC(C(N2CCN(C3=C(NC(C)C)C=CC=N3)CC2)=O)=C4)C4=C1)(C)=O

Molecular Formula

C22H28N6O3S

Molecular Weight

456.56

References & Citations

[1]Dueweke TJ, et al. U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob Agents Chemother. 1993 May;37 (5) :1127-31.|[2]Mayland Chang, et al. Metabolism of the HIV-1 Reverse Transcriptase Inhibitor Delavirdine In Mice. Research Article

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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