RBx-7796 (sodium)

RBx-7796 (sodium) is a competitive, highly selective, orally active 5-LO (IC50 = 3.5 mM for human 5-LO enzyme) inhibitor. RBx-7796 (sodium) can effectively inhibit 5-LO activity and LTB4 release. RBx-7796 (sodium) can significantly inhibit airway inflammation and bronchial constriction[1].

Product Specifications

CAS Number

[794528-96-4]

UNSPSC

12352005

Target

Lipoxygenase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O=C(O[Na])CC(C=C1)=CC=C1NC(N[C@H]([C@]2([H])[C@@]3([H])[C@@](OC(C)(C)O3)([H])[C@@H](OCCCCCCCCCCCC)O2)C)=O

Molecular Formula

C30H47N2NaO7

Molecular Weight

570.69

References & Citations

[1]Shirumalla RK, et al. Pharmacodynamic and pharmacokinetic characterisation of RBx 7796: a novel 5-lipoxygenase inhibitor. Inflamm Res. 2008 Mar;57 (3) :135-43.