RBx-7796 (sodium)
RBx-7796 (sodium) is a competitive, highly selective, orally active 5-LO (IC50 = 3.5 mM for human 5-LO enzyme) inhibitor. RBx-7796 (sodium) can effectively inhibit 5-LO activity and LTB4 release. RBx-7796 (sodium) can significantly inhibit airway inflammation and bronchial constriction[1].
Product Specifications
CAS Number
[794528-96-4]
UNSPSC
12352005
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(O[Na])CC(C=C1)=CC=C1NC(N[C@H]([C@]2([H])[C@@]3([H])[C@@](OC(C)(C)O3)([H])[C@@H](OCCCCCCCCCCCC)O2)C)=O
Molecular Formula
C30H47N2NaO7
Molecular Weight
570.69
References & Citations
[1]Shirumalla RK, et al. Pharmacodynamic and pharmacokinetic characterisation of RBx 7796: a novel 5-lipoxygenase inhibitor. Inflamm Res. 2008 Mar;57 (3) :135-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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