SAR-115740

SAR-115740 is a TRPV1 antagonist. SAR-115740 exhibits developmental toxicity in H9 cell experiments. SAR-115740 can be used for research on inflammatory conditions or neurological disorders[1].

Product Specifications

CAS Number

[1253734-75-6]

UNSPSC

12352005

Target

TRP Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC4=CC(F)=CC=C4N3CC5=CC(F)=CC=C5

Molecular Formula

C24H17F2N3O

Molecular Weight

401.41

References & Citations

[1]Khairatkar-Joshi N, et al. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol Med. 2009 Jan;15 (1) :14-22. |[2]Zurlinden TJ, et al. Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity. Toxicol Sci. 2020 Apr 1;174 (2) :189-209.