S 3578 (sulfate)

S 3578 (sulfate) is a broad-spectrum antibacterial agent, particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) (MIC = 0.78-3.13 μg/mL) and Pseudomonas aeruginosa (MIC = 1.56-6.25 μg/mL) . S 3578 (sulfate) can be used in the research of infectious conditions[1].

Product Specifications

CAS Number

[474949-70-7]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

[O-]S(=O)(O)=O.OC(C1=C(C[N+]2=C3C(N(CCCNC)C=N3)=CC=C2)CS[C@@]([C@@H]4NC(/C(C5=NSC(N)=N5)=N\OCC)=O)([H])N1C4=O)=O

Molecular Formula

C24H30N10O9S3

Molecular Weight

698.75

References & Citations

[1]Yoshizawa H, et al. New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 2: Synthesis and structure-activity relationships in the S-3578 series. Bioorg Med Chem. 2004 Aug 1;12 (15) :4211-9.