KI 1769

KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease[1][2].

Product Specifications

CAS Number

[133300-00-2]

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Smiles

N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2

Molecular Formula

C15H14N4

Molecular Weight

250.30

References & Citations

[1]Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11 (6) :561-6.|[2]Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80 (2) :143-53.