BW-1003C87 (Ethylsulfate)

BW-1003C87 Ethylsulfate is a glutamate release inhibitor. BW-1003C87 Ethylsulfate exhibit neuroprotective effect. BW-1003C87 Ethylsulfate can elevate seizure threshold. BW-1003C87 Ethylsulfate can be used for the research of neurological disease, such as ischemic and seizure[1][2][3].

Product Specifications

CAS Number

[144425-86-5]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

CCS(=O)(O)=O.NC1=NC(N)=NC=C1C2=C(C(Cl)=CC(Cl)=C2)Cl

Molecular Formula

C12H13Cl3N4O3S

Molecular Weight

399.68

References & Citations

[1]Gilland E, et al. Hypoxic-ischemic injury in the neonatal rat brain: effects of pre- and post-treatment with the glutamate release inhibitor BW1003C87. Brain Res Dev Brain Res. 1994 Nov 18;83 (1) :79-84.|[2]Morimoto K, et al. BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy. Eur J Pharmacol. 1997 Nov 19;339 (1) :11-5.|[3]Gaspary HL, et al. BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. Eur J Pharmacol. 1994 Sep 12;262 (3) :197-203.