MDL 201112
MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology[1].
Product Specifications
CAS Number
142130-73-2
UNSPSC
12352005
Target
MHC; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
NC1=NC=NC2=C1N=CN2[C@@H]3C[C@H](O)CC3
Molecular Formula
C10H13N5O
Molecular Weight
219.24
References & Citations
[1]Edwards CK 3rd, et al. Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression. J Leukoc Biol. 1994 Aug;56 (2) :133-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MHC II
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