MDL 201112

MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology[1].

Product Specifications

CAS Number

[142130-73-2]

UNSPSC

12352005

Target

MHC; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

NC1=NC=NC2=C1N=CN2[C@@H]3C[C@H](O)CC3

Molecular Formula

C10H13N5O

Molecular Weight

219.24

References & Citations

[1]Edwards CK 3rd, et al. Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression. J Leukoc Biol. 1994 Aug;56 (2) :133-44.