MDL 43291
MDL 43291 is a competitive leukotriene (LT) receptor antagonist. MDL 43291 antagonize LTD4 and LTE4 with pA2 of 6.7. MDL 43291 does not antagonize histamine, carbachol or substance P. MDL 43291 can be used for the researches of inflammation and immunology, such as asthma[1].
Product Specifications
CAS Number
129357-91-1
UNSPSC
12352005
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
OC(CS[C@H]1[C@@](O2)([H])[C@](CCC2=O)([H])CC/C1=C/CCCCCCCCCCCCC)=O
Molecular Formula
C25H42O4S
Molecular Weight
438.66
References & Citations
[1]Gieske TH, et al. Conformationally restricted leukotriene receptor antagonists: [ (octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl) thio]ace tic acids. Pharmacology. 1990;40 (5) :271-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTD4/CysLT1; LTE4
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